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Laboratory of Developmental Cell Biology and Disease

Author: From: Time: 2018/9/27 16:06:18 [Print]

Laboratory of Developmental Cell Biology and Disease


Retinal degeneration is the leading cause of blindness in the world, which still lacks effective treatments. One of the reasons is the molecular mechanisms of the retinal degeneration have not been fully understood. Our research interest is the transcriptional regulation and signaling pathways in retinal development and dysfunctions. We use the congenital retinal degeneration, age-related retinal degeneration, and stress induced retinal generation mice models, combined with cellular biology, molecular biology and high throughput assays, such as ChIP-seq, RNA-seq to elucidate the molecular and cellular mechanisms of the specific retinal degeneration.  Based on the elucidated mechanisms, we will use the gene therapy or drug treatment to treat the mice, we hope we can find effective ways to delay or slow down the retinal degeneration.

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