Publication and Fundings

Talent Recruitment

Honors gained

1994 Sofue Memorial Award, Society of Fiber Science, Japan

2003 Seikei Academic Award, Seikei Alumni Association, Japan

2011-present Council of Chemical Society of Japan, Division of Polymer Science

2013-present Editor in Chief of American Journal of Tissue Engineering & Stem Cell (Columbia International Publishing, USA)

2014-present Advisory Board of Journal of Materials Chemistry B (Royal Society of Chemistry, Impact factor=4.8)

2014-present Fellow, Royal Society of Chemistry (England)

2015-present Fellow, Taiwan Chemical Engineering Society (Taiwan)

2015-present Editor, Open Physics (Walter de Gruyter, German, Impact factor=0.8)

2016 Award of Royal Society of Chemistry, Symposium 2016 of The Japanese Society for Biomaterials (Fukuoka, Japan)

2017-present Editorial Board Member of Laboratory Investigation (Nature, Impact factor=4.3)

2017-present Editor in Chief, Progress in Bioscience and Bioengineering (USA)

2018-present Fellow, American Institute of Medical & Bioengineering (AIMBE, USA)

2018-present The Asia-Pacific (AP) Council of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-AP)

Representative Publication

1)A. Higuchi,*, et al., Stem Cell Therapies for Reversing Vision Los, Trends in Biotechnology, 35, Issue 11, 1102–1117 (2017). 13.6>

2)A. Higuchi*, et al., Polymeric design of cell culture materials that guide the differentiation of human pluripotent stem cells, Prog. Polym. Sci., 65 (2017) 83-126. 24.6>

3)Peng IC, Higuchi A,* et al., Continuous harvest of stem cells via partial detachment from thermoresponsive nanobrush surfaces, Biomaterials, 76 (2016) 76-86.

4)A. Higuchi*, et al., External stimulus-responsive biomaterials designed for the culture and differentiation of ES, iPS, and adult stem cells, Prog Polym. Sci., 39 (2014) 1585-1613. 24.6>

5)D.-C. Chen, A. Higuchi*, et al., Purification of human adipose-derived stem cells from fat tissues using PLGA/silk screen hybrid membranes, Biomaterials, 35 (2014) 4278-4287.

6)A. Higuchi*, et al., Design of polymeric materials for culturing human pluripotent stem cells: Progress toward feeder-free and xeno-free culturing, Prog. Polym. Sci., 39(7) (2014) 1348-1374. 24.6>

7)A. Higuchi*, et al., Physical cues of biomaterials guide stem cell differentiation fate, Chemical Reviews, 113 (2013) 3297-3328. 52.6> Highly Cited Paper

8)A. Higuchi*, et al., Biomimetic Cell Culture Proteins as Extracellular Matrices for Stem Cell Differentiation, Chemical Reviews, 112 (2012) 4507-4540. 52.6>

9)A. Higuchi*, et al., Biomaterials for the feeder-free culture of human embryonic stem cells and induced pluripotent stem cells, Chemical Reviews, 111 (2011) 3021-3034. 52.6>

Patents (5-6 items)

1. A. Higuchi, T. Kao, Cell culture article and methods for manufacturing thereof, USP 9,902,941 (February 27, 2018)

2. A. Higuchi, T. Kao, Cell culture article and methods for manufacturing thereof, Japan Patent JP 5944931 (June 3, 2016)

3. A. Higuchi, et al., Methods and systems for isolating, ex vivo expanding and harvesting hematopoietic stem cells, JP 5431786 (December 13, 2013)

4. Akon Higuchi, Nucleotide-transition metal complex catalyst, Japan Patent, JP 5256026 (2013, April 26)

5. A. Higuchi, et al., Methods and systems for isolating, ex vivo expanding and harvesting hematopoietic stem cells, Taiwan patent I 372180 (September 11, 2012)

6. Y. Chang, A. Higuchi, et al., Low biofouling filtration membranes and their forming method, USP 8,062,751 B2 (Nov 22, 2011)

论文 (2020年发表)

T. C. Sung, C. W. Heish, H. C. Lee, J. Y. Hsu, C. K. Wang, J. H. Wang. Y. R. Zhu, S. H. Jen, S. T. Hsu, A. H. Hirad, A. A. Alarfaj, A. Higuchi. 2020. 3D culturing of human adipose-derived stem cells enhances their pluripotency and differentiation abilities. Journal of Materials Science & Technology, In Press. (May 2020). <SCI, Impact factor= 5.040>

J. D. Pan, Y. C. Lee, H. C. Lee, T. C. Sung, S. H. Jen, L. K. Ban, D. C. Chen, S. T. Hsu, H. C, A. Higuchi. 2020. Culture and differentiation of purified human adipose-derived stem cells by membrane filtration via nylon mesh filters. J Mater Chem B, advance article. (May, 2020). <SCI, Impact factor= 5.047>

T. C. Sung, H. C. Su, Q. D. Ling, S. S. Kumar, Y. Chang, S. T. Hsu, A. Higuchi. 2020. Efficient differentiation of human pluripotent stem cells into cardiomyocytes on cell sorting thermoresponsive surface. Biomaterials, 253, 120060 (Sep, 2020). <SCI, Impact factor=10.273>.

T. C. Sung,* H. F. Li, A. Higuchi, S. S. Kumar, Q. D. Lin, Y. W. Wu, T. Burnouf, M. Nasu, A. Umezawa, K. F. Lee, H. C. Wang, Y. Chang, and S. T. Hsu. 2019. Effect of cell culture biomaterials for completely xeno-free generation of human induced pluripotent stem cells. Biomaterials, 230, 119638 (Feb, 2020). <SCI, Impact factor=10.273>.

专利：

US 14/188,704、US 15/009,845、JP 2014-007046 等

US 16/939,871 (申请中)