Representative Publications

1. Zhou, X., S. Zhang, G. Zhang, Y. Chen, Y. Lei, J. Xiang, R. Xu, J. Qu, and X. Zhou. 2020. Increased Choroidal Blood Perfusion Can Inhibit Form Deprivation Myopia in Guinea Pigs. Invest Ophthalmol Vis Sci 61:25.

2. Zhao, F., D. Zhang, Q. Zhou, F. Zhao, M. He, Z. Yang, Y. Su, Y. Zhai, J. Yan, G. Zhang, A. Xue, J. Tang, X. Han, Y. Shi, Y. Zhu, T. Liu, W. Zhuang, L. Huang, Y. Hong, D. Wu, Y. Li, Q. Lu, W. Chen, S. Jiao, Q. Wang, N. Srinivasalu, Y. Wen, C. Zeng, J. Qu, and X. Zhou. 2020. Scleral HIF-1α is a prominent regulatory candidate for genetic and environmental interactions in human myopia pathogenesis. EBioMedicine 57:102878.

3. Zhao, F., H. Wu, P.S. Reinach, Y. Wu, Y. Zhai, Y. Lei, L. Ma, Y. Su, Y. Chen, F. Li, X. Liu, N. Srinivasalu, J. Qu, and X. Zhou. 2020. Up-Regulation of Matrix Metalloproteinase-2 by Scleral Monocyte-Derived Macrophages Contributes to Myopia Development. Am J Pathol 190:1888-1908.

4. Pan, M., Z. Guan, P.S. Reinach, L. Kang, Y. Cao, D. Zhou, N. Srinivasalu, F. Zhao, J. Qu, and X. Zhou. 2020. PPARγ modulates refractive development and form deprivation myopia in Guinea pigs. Exp Eye Res 108332.

5. Huang, F., Q. Wang, T. Yan, J. Tang, X. Hou, Z. Shu, F. Wan, Y. Yang, J. Qu, and X. Zhou. 2020. The Role of the Dopamine D2 Receptor in Form-Deprivation Myopia in Mice: Studies With Full and Partial D2 Receptor Agonists and Knockouts. Invest Ophthalmol Vis Sci 61:47.

6. Srinivasalu, N., S. Zhang, R. Xu, P.S. Reinach, Y. Su, Y. Zhu, J. Qu, and X. Zhou. 2020. Crosstalk between EP2 and PPARα Modulates Hypoxic Signaling and Myopia Development in Guinea Pigs. Invest Ophthalmol Vis Sci 61:44.

7. Zhang, S., G. Zhang, X. Zhou, R. Xu, S. Wang, Z. Guan, J. Lu, N. Srinivasalu, M. Shen, Z. Jin, J. Qu, and X. Zhou. 2019. Changes in Choroidal Thickness and Choroidal Blood Perfusion in Guinea Pig Myopia. Invest Ophthalmol Vis Sci 60:3074-3083.

8. Huang, F., L. Zhang, Q. Wang, Y. Yang, Q. Li, Y. Wu, J. Chen, J. Qu, and X. Zhou. 2018. Dopamine D1 Receptors Contribute Critically to the Apomorphine-Induced Inhibition of Form-Deprivation Myopia in Mice. Invest Ophthalmol Vis Sci 59:2623-2634.

9. Jiang, L., S. Zhang, R. Chen, L. Ma, X. Wang, Y. Wen, J. Qu, and X. Zhou. 2018. Effects of the Tyrosinase-Dependent Dopaminergic System on Refractive Error Development in Guinea Pigs. Invest Ophthalmol Vis Sci 59:4631-4638.

10. Pan, M., S. Jiao, P.S. Reinach, J. Yan, Y. Yang, Q. Li, N. Srinivasalu, J. Qu, and X. Zhou. 2018. Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs. Invest Ophthalmol Vis Sci 59:5803-5815.

11. Srinivasalu, N., C. Lu, M. Pan, P.S. Reinach, Y. Wen, Y. Hu, J. Qu, and X. Zhou. 2018. Role of Cyclic Adenosine Monophosphate in Myopic Scleral Remodeling in Guinea Pigs: A Microarray Analysis. Invest Ophthalmol Vis Sci 59:4318-4325.

12. Wu, H., W. Chen, F. Zhao, Q. Zhou, P.S. Reinach, L. Deng, L. Ma, S. Luo, N. Srinivasalu, M. Pan, Y. Hu, X. Pei, J. Sun, R. Ren, Y. Xiong, Z. Zhou, S. Zhang, G. Tian, J. Fang, L. Zhang, J. Lang, D. Wu, C. Zeng, J. Qu, and X. Zhou. 2018. Scleral hypoxia is a target for myopia control. PNAS 115:E7091-e7100.

13. Zhang, S., J. Yang, P.S. Reinach, F. Wang, L. Zhang, M. Fan, H. Ying, M. Pan, J. Qu, and X. Zhou. 2018. Dopamine Receptor Subtypes Mediate Opposing Effects on Form Deprivation Myopia in Pigmented Guinea Pigs. Invest Ophthalmol Vis Sci 59:4441-4448.

14. Zhao, F., Q. Zhou, P.S. Reinach, J. Yang, L. Ma, X. Wang, Y. Wen, N. Srinivasalu, J. Qu, and X. Zhou. 2018. Cause and Effect Relationship between Changes in Scleral Matrix Metallopeptidase-2 Expression and Myopia Development in Mice. Am J Pathol 188:1754-1767.

15. Chen, S., Z. Zhi, Q. Ruan, Q. Liu, F. Li, F. Wan, P.S. Reinach, J. Chen, J. Qu, and X. Zhou. 2017. Bright Light Suppresses Form-Deprivation Myopia Development With Activation of Dopamine D1 Receptor Signaling in the ON Pathway in Retina. Invest Ophthalmol Vis Sci 58:2306-2316.

16. Zhang, H., F. Zhao, D.S. Hutchinson, W. Sun, N.J. Ajami, S. Lai, M.C. Wong, J.F. Petrosino, J. Fang, J. Jiang, W. Chen, P.S. Reinach, J. Qu, C. Zeng, D. Zhang, and X. Zhou. 2017. Conjunctival Microbiome Changes Associated With Soft Contact Lens and Orthokeratology Lens Wearing. Invest Ophthalmol Vis Sci 58:128-136.

17. Zhou, X., M.T. Pardue, P.M. Iuvone, and J. Qu. 2017. Dopamine signaling and myopia development: What are the key challenges. Prog Retin Eye Res 61:60-71.

18. Yan, T., W. Xiong, F. Huang, F. Zheng, H. Ying, J.F. Chen, J. Qu, and X. Zhou. 2015. Daily Injection But Not Continuous Infusion of Apomorphine Inhibits Form-Deprivation Myopia in Mice. Invest Ophthalmol Vis Sci 56:2475-2485.

19. Fang, F., F. Huang, R. Xie, C. Li, Y. Liu, Y. Zhu, J. Qu, and X. Zhou. 2015. Effects of muscarinic receptor modulators on ocular biometry of guinea pigs. Ophthalmic Physiol Opt 35:60-69.