Publications

1. Guan JT, Li XX, Peng DW, Zhang WM, Qu J, Lu F, D'Amato RJ, Chi ZL. MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A. Front Pharmacol. 2020; 11: 276. doi: 10.3389/fphar.2020.00276.

2. Gan YJ, Fang AW, Liu C, Liu BJ, Yang FM, Guan JT, Lan CL, Dai XD, Li T, Cao Y, Ran Y, Gong XH, Jin ZB, Cui RZ, Iwata T, Qu J*, Lu F*, Chi ZL*. Elevated plasma levels of drebrin in glaucoma patients with neurodegeneration. Front Neurosci. 2019; 13: 326. doi: 10.3389/fnins.2019.00326.

3. Chi ZL*, Adini A, Birsner AE, Bazinet L, Akula JD, D’Amato RJ*. PR1P ameliorates neurodegeneration through activation of VEGF signaling pathway and remodeling of the extracellular environment. Neuropharmacology. 2019; 148: 96-106. doi: 10.1016/j.neuropharm.2018.12.029.

4. Wang YQ, Dai XD, Ran Y, Cao Y, Lan CL, Guan JT, Liu C, Yang FM, Gan YJ, Liu BJ, Fang AW, Lin D, Gong XH, Cui RZ, Jin ZB, Qu J*, Lu F*, Chi ZL*. Circulating S100A8/A9 levels reflect intraocular inflammation in patients with uveitis. Ocul Immunol Inflamm. 2018; 1-9. doi:10.1080/09273948.2018.1538461.

5. Dai XD and Chi ZL. S100A8/A9: a potent biomarker and clinical candidate for the treatment of uveitis. Inflamm Cell Signal. 2017; 4: e1512. doi: 10.4800/ics.1512.

6. Wang Y, Zhang Z, Zhang L, Li X, Lu R, Xu P, Zhang X, Dai M, Dai X, Qu J*, Lu F*, Chi ZL*. S100A8 promotes migration and infiltration of inflammatory cells in acute anterior uveitis. Sci Rep. 2016; 6:36140. doi: 10.1038/srep36140.

7. Chi ZL*, Yoshida T, Lambris JD, and Iwata T. Suppression of Drusen Formation by Compstatin, a Peptide Inhibitor of Complement C3 activation, on Cynomolgus Monkey with Early-Onset Macular Degeneration. Adv Exp Med Biol. 2010: 703; 127-135.

8. Chi ZL, Yasumoto F, Sergeev Y, Minami M, Obazawa M, Kimura I, Takada Y and Iwata T. Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice. Hum Mol Genet. 2010:19(19); 3806-3815.

9. Chi ZL, Akahori M, Obazawa M, Minami M, Noda T, Nakaya N, Tomarev S, Kawase K, Yamamoto T, Noda S, Sasaoka M, Shimazaki A, Takada Y, Iwata T. Overexpression of Optineurin E50K Disrupts Rab8 Interaction and Leads to a Progressive Retinal Degeneration in Mice.　Hum Mol Genet. 2010: 19(13); 2606-2615.

10. Chi ZL*, Hayasaka S, Zhang XY, Cui HS, Hayasaka Y. A cholinergic agonist attenuates endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci. 2007: 48; 2719-2725.

11. Chi ZL*, Hayasaka Y, Zhang XY, Cui HS, Hayasaka S. S100A9-positive granulocytes and monocytes in lipopolisaccharide-induced anterior ocular inflammation in rats. Exp Eye Res. 2007: 84; 254-265.

12. Chi ZL*, Hayasaka S, Zhang XY, Hayasaka Y, Cui HS. Effects of rolipram, a selective inhibitor of type 4 phosphodiesterase, on lipopolisaccharide induced uveitis in rats. Invest Ophthalmol Vis Sci. 2004: 45; 2497-2502.

Funding

National Natural Science Foundation of China

81770918, 31871383, 81800841, 32000433

Zhejiang Provincial Natural Science Foundation

LY16H120006, LQ17H120006, LY18H120004, LQ18H120006