Publication and Fundings

Talent Recruitment

Representative publications

1.Overexpression of d-amino acid oxidase prevents retinal neurovascular pathologies in diabetic rats. Diabetologia 2020 (DOI: 10.1007/s00125-020-05333-y).

2.Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2. Mol Neurobiol 2020 Nov;57(11):4417-4437.

3. Sp4 controls constitutive expression of neuronal serine racemase and NF-E2-related factor-2 mediates its induction by valproic acid. Biochim Biophys Acta Gene Regul Mech 2020 Sep;1863(9):194597.

4. MicroRNA-29 Enhances Autophagy and Cleanses Exogenous Mutant αB-crystallin in Retinal Pigment Epithelial Cells. Exp Cell Research. 2019. Jan 1;374(1):231-248.

5. Autophagic Degradation of Stromal Interaction Molecule 2 Mediates Disruption of Neuronal Dendrites by Endoplasmic Reticulum Stress. J Neurochem. 2019 Nov;151(3):351-369.

6. Loss-of-function mutation of serine racemase attenuates retinal ganglion cell loss in diabetic mice. Exp Eye Res 2018 Oct;175:90-97.

7. Serine racemase deficiency attenuates choroidal neovascularization and reduces nitric oxide and VEGF levels by retinal pigment epithelial cells. J Neurochem, 2017.143(3): 375-388.

8. Inhibition of store-operated calcium entry by sub-lethal levels of proteasome inhibition is associated with STIM1/STIM2 degradation. Cell Calcium,2016, 59(4):172-180.

9.Roles of NFκB-miR-29s-MMP-2 circuitry in experimental choroidal neovascularization. J Neuroinflammation. 2014 May 15;11:88.

10. Pretreatment with Proteasome Inhibitors Protects against Oxidative Injuries via PPARα-Dependent and -Independent Pathways in ARPE-19 Cells. Investigative Ophthalmology & Visual Science, 2012,53(9):5967-5974.

11. Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy. Journal of Neuroinflammation, 2011,8:119.

Fundings

National Natural Science Foundation of China（81371027，81600750，81600755）

Qianjiang Scholar Scheme（QJD1202020）

Zhejiang Province Natural Science foundation（LY18H120003，LQ18H090005，LQH100004，LQ16C060002， LQ14C060002，Y2110086）

Chinese Ministry of Education（20133321120002）